Single gene sequencing? MLPA?


In addition to the latest high-throughput sequencing, we also offer a broad spectrum of other methods such as Sanger sequencing or MLPA (multiplex ligation-dependent probe amplification) for the diagnosis of a variety of diseases and syndromes. Here you will find a selection of these analyses for the selected indication area. Please contact us if you have any questions or if you cannot find the analysis you are looking for in the list.

Gene/chromosomal region Disease Method Material (if different from 3-5 ml EDTA or 1-5 µg DNA) TAT (weeks)
BCR-ABL1 leukemia (BCR-ABL1, qualitativ) Fragment analysis 2 x 4-5 ml fresh EDTA-blood or 4-5 ml fresh EDTA bone marrow 2
BCR-ABL1 leukemia (BCR-ABL1, quantitative) Real-time PCR 2 x 4-5 ml fresh EDTA-blood or 4-5 ml fresh EDTA bone marrow 2
BCR-ABL1 p190 leukemia (BCR-ABL1 p190, quantitative) Real-time PCR 2 x 4-5 ml fresh EDTA-blood or 4-5 ml fresh EDTA bone marrow 2
PML-RARA leukemia, acute promyelocytic (PML-RARA, qualitative) Fragment analysis 2 x 4-5 ml fresh EDTA-blood or 4-5 ml fresh EDTA bone marrow 1
PML-RARA leukemia, acute promyelocytic (PML-RARA, quantitative) Real-time PCR 2 x 4-5 ml fresh EDTA-blood or 4-5 ml fresh EDTA bone marrow 1
JAK2, exon 14 neoplasm, myeloproliferative (JAK2, exon 14, V617F) Real-time PCR 4-5 ml EDTA blood 1-2
JAK2, exon 12 neoplasm, myeloproliferative (JAK2, exon 12) Sanger sequencing 4-5 ml EDTA blood 1-2
CALR, exon 9 neoplasm, myeloproliferative (CALR) Sanger sequencing 4-5 ml EDTA blood 1-2
MPL, exon 10 neoplasm, myeloproliferative (MPL) Sanger sequencing 4-5 ml EDTA blood 1-2