Hematooncology

In addition to the diagnosis of hereditary blood diseases, genetic diagnostics also provides support in hematological neoplasms. The detection of specific gene alterations (molecular genetics) as well as disease-typical chromosomal aberrations (cytogenetics and FISH) plays an important role in

• the differential diagnostic evaluation,
• the assessment of prognosis
• therapy planning and
• monitoring the course of therapy.

To meet the requirements of these complex diseases, we rely on interdisciplinary, comprehensive diagnostics from special hematology, molecular genetics and cytogenetics in the diagnosis of leukemias and lymphomas. In our laboratory, we offer the entire spectrum of tumor-genetic examinations:

• Chromosome analysis (if necessary with indication-specific stimulation)
• Fluorescence in situ hybridization (FISH) (if necessary on enriched CD138+ cells)
• Analysis of hotspot variants
• RNA-based fusion gene analyses
• NGS panel analyses
• MRD progression controls
• Immunophenotyping
• Microscopy of hematological systemic diseases

We guarantee comprehensive interdisciplinary diagnostics from a single source. In cooperation with Molecular Pathology Trier, we also offer molecular pathological diagnostics of solid tumors.

Personalized diagnostics is an essential step in supporting targeted therapy. Based on the genetic changes found in the tumor, treating physicians adapt therapies individually, which can improve the chances of cure.

If you have any questions about genetics in hemato-oncology, please do not hesitate to contact us.